UCI Team Finds Method to Reduce Accumulation of Damaging Huntington’s Disease Protein

A study appearing April 14 in the journal Neuron suggests there may be a new way to change the damaging course of Huntington disease. University of California, Irvine neurobiologists Leslie Thompson and Joseph Ochaba and their colleagues from UCI and from Children’s Hospital of Philadelphia have shown that reducing the aberrant accumulation of a particular form of the mutant Huntingtin protein corresponds to improvement in symptoms and neuroinflammation in HD mice. Read more

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